Contact person
Matilda Bäckberg
Enhetschef
Contact Matilda
Preclinical inhalation studies
Are you running a project for new inhalation drugs or studying airborne pollutants? We offer complete solutions with high quality and versatile expertise in inhalation exposure so that you as a customer will receive the best service.
We offer
For substances that are to be administered via inhalation:
- Pharmacokinetic (PK) studies
- Efficacy studies, such as inflammation models
Our system
PreciseInhale®
The PreciseInhale® system can be used to administer substances either to intratracheally intubated animals under anesthesia, or to unanaesthetised or sedated animals by nose-only. The exposure system enables use of both nebulization of liquids or dry powder aerosols of test substances.
Our analyses
In accordance with guidelines, eg OECD TG412, we perform:
- Aerodynamic characterization of substances (MMAD; mass median aerodynamic diameter, GSD; geometric standard deviation)
- Chemical analysis for calculation of inhalation dose, bioanalysis
- Bronchoalveolar lavage (BAL) for analysis of cells, cytokines, proteins and Blood Urea Nitrogen (BUN)
- Macroscopic and microscopic pathology
